New breakthrough in hemophilia research: saliva activates coagulation!

New breakthrough in hemophilia research: saliva activates coagulation!

A groundbreaking study by the MedUni Vienna has opened up new perspectives on blood clotting in hemophilia A, a frequent form of blood disease. Researchers: Inside around Johannes Thaler and Cihan Ay, found that the saliva of hemophilia A-patient: Inside, contains special cell structures that enable faster blood clotting. These findings have currently been published in the journal "Blood" and underline the essential role of body fluids for blood clotting - a topic that has been forgotten since the 1930s when the coagulation -promoting properties of breast milk were discovered. "They therefore often suffer from mouth bleeding," explains Thaler, who indicates the absence of protective mechanism in other patients, as Das Klinikum Nürnberg supplemented.

historical findings re -evaluated

The identification of the extrinsic tenase complexes in saliva could finally provide answers to why hemophilia patients are more likely to suffer from mucosal bleeding inside than on joint bleeding. The researchers: Inside, the historical knowledge of blood clotting from breast milk, amniotic fluid and urine has taken up and discovered that these body fluids are due to the same cell structures for their coagulation -promoting properties. This could open up new ways for innovative treatment methods to treat hemophilia A more effectively - a topic that arouses interest not only from scientists: inside, but also from clinicians who are closely with specialist departments such as hemostasology in Klinikum Nürnberg work together.

Due to the findings, not only the medical community learns new impulses, but also patient care could benefit considerably. This study helps to expand the understanding of blood clotting mechanisms that may lead to more efficient therapies for hemophilia A in the future.