Bielefeld students revolutionize gene therapy against cystic fibrosis!

Bielefeld students revolutionize gene therapy against cystic fibrosis!

An innovative student research team from the University of Bielefeld specializes in the development of genetic therapy for the treatment of cystic fibrosis, a frequent genetic illness. This disease is caused by genetic mutations in the CFTR gene, which is responsible for the transport of chloridions into cells. The students are part of the IGEG competition, which is considered the largest international competition in the field of synthetic biology. From October 23 to 26, their results will be presented at the Grand Jamboree in Paris, where they compete with over 450 teams from all over the world.

This year's group called "Precys" works on improving gene therapy to treat the most common mutation in the CFTR gene. This mutation leads to a malfunction of the ion channel, which leads to serious respiratory diseases. The team relies on "Prime Editing", a precise method that enables generous changes. This could help improve patients in the long term by treating the underlying cause of the disease.

engagement beyond the research laboratory

The 13-member team not only works in the laboratory, but is also active outside of it. Through discussions with those affected, doctors and scientists, they collect valuable practical insights that flow into their project. In order to promote the exchange between the European Igem teams, they organized events such as the BFH European Meetup in Bielefeld.

Participation in the IGEG competition offers students the opportunity to learn in various disciplines such as laboratory technology, web design and public relations. Your interdisciplinary approach brings together competencies from areas such as biology and media sciences, which is of great importance for the presentation of your project. They hope that their work is driving the development of gene therapies and enables more secure and effective treatments.

The IGEG competition has developed into an important platform for students since its foundation in 2004 who want to realize their own projects in the field of synthetic biology. Not only the laboratory work is evaluated, but also dealing with social, economic and safety -relevant questions that every project should accompany.

For more information, See the current report current.uni-bielefeld.de .