Scientists develop medication in silk packaging for patients
Scientists develop medication in silk packaging for patients
Thailand has been known for the production of become. However, the latest research from biomedal zenzi of the Chulalongkorn University in Bangkok shows that the silk can also find an innovative application in medication.
The role of silk fibroin in drug levy
medication tax systems exist in many forms, from capsules and tablets to skin plasters and injections. According to Juthama's Ratanavaraporn, director of the biomedical research center at the Chulalongkorn University, Seidenfibroin-a natural protein that gives the silk its incredible strength-can be used in a sacular form to enclose medication. This shape decomposes more slowly than other natural proteins such as gelatin or chitosan and ensures a slow release of the medication in the body.
controlled medication release
"Instead of needing large or frequent doses, the protein capsule can gradually release the drug in the appropriate quantities that the body needs. This controlled release helps to reduce the total dose and the risk of side effects," explains Ratanavaraporn.
The foundation of Enginelife
After 17 years of research, Ratanavaraporn founded the Enginelife company with two other professors from her team with two other professors from her team. This start-up company produces a first approved product line-a treatment plaster for insomnia-which was launched in Thailand.
Silk fibroin: A versatile material
Silkenfibroin has been over a century examined, especially with regard to biomedical applications. It is biocompatible, sustainable and cost -effective, which as a medication wearer it makes advantage of other materials. "The structure of silk fibroin, in particular the strong and stable beta folding sheet, allows slow and controlled medication release and gives it flexibility and strength," says Mingying Yang, a research manager at the Zhejiang University in China.
challenges in product development
Although silk fibroin was examined for a variety of applications - from bone substrates to corneal grids - only a few products have reached the market. A Scientific overview from 2022 have achieved clinical tests.
Standardization of silk quality
A big problem in silk production is the variability of the material. In Thailand, the silk often comes from small, family -run farms and is produced by silk cocks, whose feed and climate can have fluctuations that influence the quality of the silk. To overcome this, Enginelife experiment with various cultivation methods and has introduced strict standards to ensure the quality of silk production.
Future developments in the field of drug levy
Currently Farm produces around 25-30 kilograms of silk cocoons annually, which can be used millions of applications millions of applications. The company focuses on the development of new products, including transdermal pavement and injectable hydrogels against osteoarthritis. Ratanavaraporn believes that silk fibroin can be used in many other medication tax systems to help patients and at the same time to offer the silk farmers in Thailand a new source of income.
"Silk already has a high value as a fabric, but now we position it as a medical material, which at least tenenses its value," concludes Ratanavaraporn.
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