Breakthrough: First tests for the pill for men show promising results!

Breakthrough: First tests for the pill for men show promising results!

The discussion about contraceptives for men gradually gains dynamics, especially through the development of a new drug called YCT-529. This innovative product is currently being tested clinically and could offer a safe, hormone -free alternative to the existing contraception in the future, which is still mainly the responsibility of women. According to oe24 the antibabopill is still the most popular contraceptive to women, even if the use of 42 percent of women has been determined. Densified by condoms that are 40 percent.

Research behind YCT-529 is managed by YOANKOICE therapeutics and mainly includes British subjects. The Results 99 percent is effective in preventing pregnancy and is completely reversible, without any noteworthy side effects. Male test subjects could get their fertility back within four to six weeks after stopping the pill.

scientific foundations and successes

yct-529 works as an inhibitor of the retinic acid receptor Alpha, which blocks access to vitamin A, an essential nutrient for spermatogenesis. This knowledge is important because previous studies have shown that vitamin A is crucial for male reproduction. In preclinical experiments on mice, there was a remarkable effectiveness: the pregnancy rates in females decreased by almost 100 percent, which underpins the high expectations of YCT-529. The effect occurred within one month, convincing for both mice and macaques. These results could have the potential to significantly expand the currently limited men's prevention - which consists mainly of condoms and vasectomies.

Market research estimates the potential of new male contraceptives for a value between $ 40 and 200 billion, taking around 10 million men in the USA and 50 million worldwide, which would be willing to use a pill. A survey from 2021 showed that 34 to 82.3 percent of men were willing to use male contraceptives.

Current contraceptive methods and their challenges

Currently, only a few contraceptive methods are available to men. Condoms are very popular as the most frequently used method, since they also offer protection against sexually transmitted diseases. However, they are not without challenges in their use. The correct use includes several steps that must be observed to ensure effectiveness. Incorrect application can significantly impair reliability, which often leads to unwanted pregnancies.

• vasectomy: This method is a form of sterilization and is often considered more uncomplicated than in women, but is not easily reversible.
• Scrin therapies: There are hormonal injections such as testosterone injections that have to be repeated every 30 days, but can result in side effects such as acne and mood swings.
• Innovative approaches: Power underpants and prototypes for new hormonal options show that research is progressing, but many of these methods are faced with regulatory and social challenges.